重组小鼠干扰素γ(Murine IFN-γ)是一种由CD4和CD8 T淋巴细胞以及活化的NK细胞产生的一种不稳定的干扰素。IFN-γ受体存在于大多数免疫细胞中,它们通过增加Ⅰ类γ蛋白的表面表达来响应IFN-γ信号传导。使用 WEHI-279 细胞通过细胞毒性试验测定的ED50 < 0.15 ng/ml。可用于构建斑秃动物模型。
别名:IFN gamma
重组小鼠干扰素γ(Murine IFN-γ)是一种由CD4和CD8 T淋巴细胞以及活化的NK细胞产生的一种不稳定的干扰素。IFN-γ受体存在于大多数免疫细胞中,它们通过增加Ⅰ类γ蛋白的表面表达来响应IFN-γ信号传导。干扰素-γ信号在抗原提呈、细胞和抗原识别B、T淋巴细胞中,调节抗原特异性免疫应答期。此外,干扰素-γ刺激了许多淋巴细胞功能,包括巨噬细胞、NK细胞和中性粒细胞的抗微生物和抗肿瘤反应。
使用 WEHI-279 细胞通过细胞毒性试验测定的ED50 < 0.15 ng/ml。
复溶后,本品在4°C下应可稳定1周,或在-20°C下可稳定3个月。对于长期储存,建议加入载体蛋白(如0.1% BSA)。避免反复冻融。
Recombinant mouse IFN-γ expressed the target gene encoding His23-Cys155.
Accession: P01580
Endotoxin < 1 EU/µg
Apparent Molecular Weight: ~15 KDa, reducing conditions
Lyophilized after extensive dialysis against PBS.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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