—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

Anti-human HER-2 mAb 抗人HER-2单克隆抗体

目录号 M11384 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


生物活性:HER2 又称 ErbB2,是人类表皮生长因子受体家族的成员之一,具有重要的信号转导作用。

Anti-human HER-2 mAb结构式
规格 价格 库存状态
500ug ¥ 4050 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >98% , Endotoxin <2EU/mg
  • COA
  • MSDS
生物活性

表达宿主:CHO 细胞

内毒素:<2EU/mg

纯度:>98%

浓度:1mg/mL

存储及稳定性:启封后置于-20℃保存期 6 个月, -80℃保存期 12 个月。 避免反复冻融


生物活性:HER2 又称 ErbB2,是人类表皮生长因子受体家族的成员之一,具有重要的信号转导作用。Her-2/neu 蛋白介导的信号转导途径主要有 Ras/Raf/分裂素活化蛋白激酶(MAPK)途径,磷脂酰肌醇.3 羟基激酶(P13K)/Akt 途径,信号转导及转录激活(STAT)途径和 PLC 通路等。2 Her-2/neu 蛋白在胃癌中的表达情况及影响因素 Her-2/neu 蛋白通常只在胎儿时期表达,成年以后只在极少数组织内低水平表达。

化学性质
储存条件 粉末型式       -20°C   3年;4°C   2年
溶于溶剂       -80°C   6个月;-20°C   1个月
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Yukinari Kato, et al. Monoclon Antib Immunodiagn Immunother. An Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H 2 Mab-19 Exerts Antitumor Activity in Mouse Colon Cancer Xenografts

[2] Yukinari Kato, et al. Monoclon Antib Immunodiagn Immunother. H 2 Mab-19 Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody Therapy Exerts Antitumor Activity in Pancreatic Cancer Xenograft Models

[3] Yukinari Kato, et al. Monoclon Antib Immunodiagn Immunother. Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody H 2 Mab-41 Exerts Antitumor Activity in a Mouse Xenograft Model of Colon Cancer

[4] Mohammad Mehdi Amiri, et al. Iran J Immunol. Development of a Novel Inhibitory Chimeric Anti-HER2 Monoclonal Antibody

[5] Shinji Yamada, et al. Monoclon Antib Immunodiagn Immunother. Establishment of H 2 Mab-119, an Anti-Human Epidermal Growth Factor Receptor 2 Monoclonal Antibody, Against Pancreatic Cancer

100%好运必中
ChemBridge—化合物库中的金标准
  获取最新目录册
Abmole最新目录册
其他相关的Recombinant Proteins产品
Recombinant Mouse Lumican (Mammalian, C-6His)

Lumican binds to laminin. It has positive regulation of transcription from RNA polymerase II promoter and transforming growth factor beta1 production.

Recombinant Human Serpin A12 (E.coli, N-GST)

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.

Recombinant Human B2M Protein (Mammalian, C-6His)

β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.

Recombinant Mouse E-Selectin/CD62E Protein (HEK293)

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.

Recombinant Human DPP4/CD26 (Mammalian, C-6His)

DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.





关键词:Anti-human HER-2 mAb, Anti-human HER-2 mAb供应商, Recombinant Proteins抑制剂, 购买Anti-human HER-2 mAb, Anti-human HER-2 mAb溶解度, Anti-human HER-2 mAb结构式








021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号