Immunology/Inflammation 抑制剂/激活剂/调节剂 Immunology/Inflammation

目录号	产品名称	产品简介
M4614	Orientin	Orientin（荭草苷）是一种可从药用植物中分离的生物活性化合物，能有效地抑制Sortase A的活性，其IC50为50.44 ± 0.51 µM。还可以通过Nrf2以及JNK/cytochrome c/caspase-3信号通路，抑制APAP诱导的肝细胞氧化损伤和线粒体功能障碍，具有抗氧化，抗炎和抗癌活性。
M9358	ITE	ITE是一种有效的，内源性的芳烃受体（AhR）的激动剂，可直接与AhR结合，Ki为3 nM。
M10093	α-Galactosyl Ceramide	α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) α-半乳糖神经酰胺是一种强大的NKT细胞刺激剂，和选择性CD1d配体。α-Galactosylceramide (α-GalCer) 是一种合成的糖脂，具有抗肿瘤和免疫刺激作用。
M1831	Cyclosporine A	Cyclosporin A（环胞菌素，环孢菌素，环胞霉素A，环孢素A，环蒽孢A，环孢素）是一种由11个氨基酸组成的环状非核糖体肽，同时也是一种大环类化合物，可与亲环蛋白18(Cyp18)结合，抑制钙调神经磷酸酶(CaN)的活性，IC50值为7 nM。此外，Cyclosporin A还能抑制T细胞活化，具有免疫抑制活性，可用于干眼症、类风湿性关节炎和银屑病的相关研究。
M20413	4-Biphenylacetic acid	4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
M25413	Fucoxanthin	岩藻黄质 Fucoxanthin 是一种天然存在于某些藻类中的类胡萝卜素，具有抗肥胖、抗氧化、抗糖尿病、抗癌和抗炎活性。
M31316	DiaPep277	DiaPep277 是一种基于热休克蛋白60（HSP60）437至460残基的，包含24个氨基酸的肽，可用于1型糖尿病免疫系统的相关研究。
M29608	MRS4620	MRS4620 是一种有效的 CD73 抑制剂，Ki 值为 0.436 nM。MRS4620 可用于癌症免疫研究的研究。
M21029	MRE-269(ACT-333679)	MRE-269(ACT-333679) is a prostaglandin I2 (IP) receptor agonist with a binding affinity for the human IP receptor that is 130-fold greater than that for other human prostanoid receptor.
M21012	Loxoprofen Sodium	Loxoprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group
M20970	Adelmidrol	Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
M20960	Tinoridine hydrochloride	Tinoridine hydrochloride is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.
M20939	Diclofenac Epolamine	Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.
M20675	Etofenamate	Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
M20667	Anisodamine Hydrobromide	Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
M20567	Salicylamide	Salicylamide is a non-prescription drug with analgesic and antipyretic properties.
M20561	Picolinic acid (PCL 016)	PCL016 is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.
M20544	Trans-Tranilast	Trans-Tranilast可用于支气管哮喘，过敏性鼻炎和特应性皮炎的相关研究。
M20536	Setipiprant (ACT-129968, KYTH-105)	Setipiprant(ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1.
M20448	Actarit	Actarit is an orally active immunomodulator used in the treatment of rheumatoid arthritis.
M20418	Dehydroandrographolide Succinate Potasium Salt	Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.

信号通路

产品类型

Immunology/Inflammation 抑制剂/激活剂/调节剂 Immunology/Inflammation

AbMole

服务与支持

技术资源

联系我们