血管内皮生长因子 (VEGF) 是一种有效的生长和血管生成细胞因子。它刺激内皮细胞的增殖和存活，并促进血管生成和血管通透性。Accession # P15692-4。ED50为1.0 ~ 5.0 ng/ml，通过剂量依赖性刺激HUVEC细胞增殖，对应的比活性为2.0 × 105 ~ 1.0 × 106 units/mg。
别名：VEGF-165; Vascular Endothelial Growth Factor 165; VPF
表达系统：P. pastoris
纯度：SDS-PAGE分析> 95%
内毒素水平：凝胶凝血法测定蛋白质< 0.5 EU/μg
表观分子量：~ 38- 40kda，在非还原条件下SDS-PAGE
~ 18- 20kda，在SDS-PAGE还原条件下
剂型：Lyophilized after extensive dialysis against 25 mM HEPES, 150 mM NaCl, pH 7.0.
存储及稳定性：在接收后，该产品在低于-70°C的环境下保持稳定长达6个月。重组后，产品应在4°C下稳定1周或在-20°C下稳定3个月。为了长期保存，建议添加载体蛋白(如0.1% BSA)。避免反复的冻融循环。
生物活性：血管内皮生长因子(VEGF)（P. pastoris)是一种有效的生长和血管生成细胞因子。刺激内皮细胞增殖和存活，促进血管生成和血管通透性。血管内皮生长因子(VEGF)表达于血管化组织，在正常和病理性血管生成中发挥重要作用。大量证据表明血管内皮生长因子(VEGF)在肿瘤转移和眼内新生血管综合征的诱导中起着重要作用。血管内皮生长因子(VEGF)信号通过三个受体传递;fms样酪氨酸激酶(flt-1)、KDR基因产物(小鼠KDR的同源物是flk-1基因产物)和flt4基因产物。
| 溶解性（25°C） | Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml |
| 储存条件 | Stable for up to 6 months at lower than -70°C after receipt |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
| 其他相关的Recombinant Proteins产品 |
|---|
| Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
| Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
| Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
| Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
| Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
产品仅供科学研究或药证申报的用途使用，不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号
蛋白质研究