IL-2 是一种强大的免疫调节淋巴因子，由 T 细胞响应抗原性或促有丝分裂刺激而产生。
别名：rMuIL-2
IL-2 是一种强大的免疫调节淋巴因子，由 T 细胞响应抗原性或促有丝分裂刺激而产生。IL-2/IL-2R 信号是 T 细胞增殖和其他免疫反应必不可少的基本功能所必需的。IL2 受体由三个亚基组成（55 kDa IL2Rα、75 kDa IL2Rβ、64 kDa 共同伽马链 γc/IL2Rγ），它们以不同的预制复合物形式存在于细胞表面；成熟小鼠 IL2 与人和大鼠 IL2 分别具有 56% 和 73% 的氨基酸序列同一性。小鼠和人 IL2 表现出跨物种活性。小鼠 IL2 有一个特定的 N 端区域，其中包含一个聚谷氨酰胺（包含 12 个谷氨酰胺）片段。
通过使用鼠 CTLL-2 细胞的细胞增殖测定法测定的 ED50小于 0.2 ng/ml，对应于 > 5.0 × 106 IU/mg的比活性。
Source: E. coli
| 溶解性（25°C） | Water Saline PBS |
| 储存条件 |
粉末型式 -20°C 3年；4°C 2年 溶于溶剂 -80°C 6个月；-20°C 1个月 |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
| 其他相关的Recombinant Proteins产品 |
|---|
| Recombinant Human Serpin A12 (E.coli, N-GST)
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. |
| Recombinant Human B2M Protein (Mammalian, C-6His)
β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. |
| Recombinant Mouse E-Selectin/CD62E Protein (HEK293)
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis. |
| Recombinant Human DPP4/CD26 (Mammalian, C-6His)
DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. |
| Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
产品仅供科学研究或药证申报的用途使用，不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号
蛋白质研究