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Recombinant Mouse MFGE8 Protein (HEK293, C-6×His) 重组小鼠MFGE8蛋白 (HEK293, C-6×His)

目录号 M40767 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Mouse MFGE8 Protein contributes to phagocytic removal of apoptotic cells in many tissues. It plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.

Recombinant Mouse MFGE8 Protein (HEK293, C-6×His)结构式

别名:MFGM

规格 价格 库存状态
10ug ¥ 1710 中国库存现货
50ug ¥ 5580 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >85%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
生物活性

Mouse MFGE8 Protein contributes to phagocytic removal of apoptotic cells in many tissues. It plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. MFGE8 binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. MFGE8 promotes VEGF-dependent neovascularization.

The protein has a predicted molecular mass of 49.8 kDa after removal of the signal peptide. The apparent molecular mass of mMFGE8-His is approximately 55-70 kDa due to glycosylation.


Accession: P21956

Endotoxin < 1 EU/μg

Lyophilized from sterile PBS, pH 7.4.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 1 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Yuheng Lu et al. Cell Death Dis. MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway

[2] Tian Tian et al. Theranostics. Targeted delivery of neural progenitor cell-derived extracellular vesicles for anti-inflammation after cerebral ischemia

[3] Kehong Chen et al. J Immunol. Inhibition of Efferocytosis by Extracellular CIRP-Induced Neutrophil Extracellular Traps

[4] Yong-Yue Gao et al. Exp Neurol. MFG-E8 attenuates inflammation in subarachnoid hemorrhage by driving microglial M2 polarization

[5] Ke-Qiong Deng et al. Hypertension. Restoration of Circulating MFGE8 (Milk Fat Globule-EGF Factor 8) Attenuates Cardiac Hypertrophy Through Inhibition of Akt Pathway

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