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Recombinant Mouse IL-34 Protein (HEK293, C-His) 重组小鼠IL-34蛋白 (HEK293, C-His)

目录号 M31295 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


IL-34 是一种细胞因子,可通过集落刺激因子-1 受体 (CSF1R) 促进单核细胞和巨噬细胞的分化和活力。在使用 M-NFS-60 小鼠髓系细胞进行的细胞增殖试验中,测定的ED50为50-200 ng/mL。

Recombinant Mouse IL-34 Protein (HEK293, C-His)结构式

别名:Interleukin 34

规格 价格 库存状态
50ug ¥ 5580 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >90%, Endotoxin < 1 EU/μg
  • COA
  • MSDS
生物活性

IL-34 是一种细胞因子,可通过集落刺激因子-1 受体 (CSF1R) 促进单核细胞和巨噬细胞的分化和活力。在使用 M-NFS-60 小鼠髓系细胞进行的细胞增殖试验中,测定的ED50为50-200 ng/mL。


表观分子量:38kDa,还原条件

内毒素< 1 EU/μg

剂型描述:从 0.2 μm 过滤的 PBS 溶液中冻干,pH 7.4。

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Huiqing Yang, et al. Clin Exp Rheumatol. Il-34 regulates MAPKs, PI3K/Akt, JAK and NF-κB pathways and induces the expression of inflammatory factors in RA-FLS

[2] Carolina Duarte, et al. Biochem Biophys Res Commun. Age-dependent effects of the recombinant spike protein/SARS-CoV-2 on the M-CSF- and IL-34-differentiated macrophages in vitro

[3] Séverine Bézie, et al. Front Immunol. IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection

[4] Li Zhang, et al. J Interferon Cytokine Res. Interleukin-34 Aggravates the Severity of Arthritis in Collagen-Induced Arthritis Mice by Inducing Interleukin-17 Production

[5] Zhi Chen, et al. PLoS One. The critical role of IL-34 in osteoclastogenesis

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