Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.
别名:aldesleukin; interleukin 2; interleukin-2
白细胞介素2 (Interleukin 2, IL 2),又称t细胞生长因子。IL-2信号通过IL-2受体传递,IL-2受体是一个由树形亚基组成的复合物,被称为alpha, beta和gamma。成熟小鼠IL-2与人IL-2和大鼠IL-2的同源性分别为56%和73%。IL-2由CD4+ T细胞、CD8+ T细胞、γ δ T细胞、B细胞、树突状细胞和嗜酸性粒细胞产生,主要通过其对T细胞的强大刺激活性,在免疫系统、耐受和免疫的关键功能中发挥重要作用。因此,IL-2可能是自然抑制自身免疫的关键细胞因子。
Recombinant Mouse Interleukin-2 is produced by E.coli expression system, and expressed the target gene encoding Ala21-Gln169.
Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells, the specific activity of Recombinant Mouse IL-2 is ≥1×107 IU/mg.
Accession: P04351
Endotoxin < 0.01 EU/µg
Apparent Molecular Weight: 17 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM Sodium Citrate, 0.2% Tween 80, pH 3.0.
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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