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Recombinant Mouse IL-2 (E.coli) 重组小鼠IL-2蛋白 (E.coli)

目录号 M19999 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.

Recombinant Mouse IL-2 (E.coli)结构式

别名:aldesleukin; interleukin 2; interleukin-2

规格 价格 库存状态
10ug ¥ 1395 中国库存现货
50ug ¥ 4140 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.01 EU/µg
  • COA
  • MSDS
生物活性

白细胞介素2 (Interleukin 2, IL 2),又称t细胞生长因子。IL-2信号通过IL-2受体传递,IL-2受体是一个由树形亚基组成的复合物,被称为alpha, beta和gamma。成熟小鼠IL-2与人IL-2和大鼠IL-2的同源性分别为56%和73%。IL-2由CD4+ T细胞、CD8+ T细胞、γ δ T细胞、B细胞、树突状细胞和嗜酸性粒细胞产生,主要通过其对T细胞的强大刺激活性,在免疫系统、耐受和免疫的关键功能中发挥重要作用。因此,IL-2可能是自然抑制自身免疫的关键细胞因子。

Recombinant Mouse Interleukin-2 is produced by E.coli expression system, and expressed the target gene encoding Ala21-Gln169.

Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells, the specific activity of Recombinant Mouse IL-2 is ≥1×107 IU/mg.


Accession: P04351

Endotoxin < 0.01 EU/µg

Apparent Molecular Weight: 17 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM Sodium Citrate, 0.2% Tween 80, pH 3.0.

使用AbMole产品发表的文献
化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Jianlin Chen, et al. Biology (Basel). Co-Expression of Pig IL-2 and Fusion Bovine Cathelicidin Gene by Recombinant Plasmids in Yeast and Their Promotion of Mouse Antibacterial Defense

[2] Elham Adabi, et al. Iran Biomed J. Evaluation of an Albumin-Binding Domain Protein Fused to Recombinant Human IL-2 and Its Effects on the Bioactivity and Serum Half-Life of the Cytokine

[3] Can Xu, et al. World J Gastroenterol. Construction of recombinant attenuated Salmonella typhimurium DNA vaccine expressing H pylori ureB and IL-2

[4] V Bronte, et al. J Immunol. IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases

[5] C M Roifman, et al. Cell Immunol. Functional comparison of recombinant interleukin 2 (IL-2) with IL-2-containing preparations derived from cultured cells

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关键词:Recombinant Mouse IL-2 (E.coli), aldesleukin; interleukin 2; interleukin-2, Recombinant Mouse IL-2 (E.coli)供应商, Recombinant Proteins抑制剂, 购买Recombinant Mouse IL-2 (E.coli), Recombinant Mouse IL-2 (E.coli)溶解度, Recombinant Mouse IL-2 (E.coli)结构式








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