Fibroblast Growth Factor-10 (FGF-10, also known as KGF-2) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions.
别名：Fibroblast Growth Factor-10; FGFA; Keratinocyte growth factor-2
Fibroblast Growth Factor-10 (FGF-10, also known as KGF-2) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development.
Measured by a cell proliferation assay using 4MBr-5 cells, the ED50 is < 10.0 ng/ml, corresponding to a specific activity of > 1.0 × 105 units/mg.
Accession: O35565
Apparent Molecular Weight: ~17 kDa, reducing conditions
Endotoxin < 0.2 EU/μg
Lyophilized after extensive dialysis against PBS.
| 性状 | Lyophilized powder |
| 溶解性（25°C） | Reconstitute the lyophilized powder in ddH2O to 100 μg/ml. |
| 储存条件 | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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