—更好的抑制剂,金标准的化合物库
致电  021-50967598
或联系  在线客服QQ

Recombinant Human Sonic Hedgehog/Shh (E.coli) 重组人Sonic Hedgehog/Shh蛋白 (E.coli)

目录号 M15057 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


重组人 Sonic Hedgehog 由大肠杆菌表达系统生产,并表达编码 Cys24-Gly197 的靶基因。

Recombinant Human Sonic Hedgehog/Shh (E.coli)结构式

别名:SHH; HHG-1

规格 价格 库存状态
10ug ¥ 1665 中国库存现货
50ug ¥ 4860 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.01 EU/ug
  • COA
  • MSDS
生物活性

Sonic Hedgehog Homolog (SHH) 属于刺猬三种蛋白质家族。其他两个家族成员是印度刺猬(IHH)和沙漠刺猬(DHH)。刺猬蛋白是胚胎发育的关键信号分子。SHH在多种胚胎组织中表达,在调节肢体和大脑等许多系统的模式方面发挥着关键作用。SHH在成人中也起着重要作用,包括成人干细胞的分裂以及某些癌症和其他疾病的发生。SHH-N具有“全信号”能力。SHH-N与细胞表面的12通跨膜蛋白Patched (Ptc)结合,释放Ptc对g蛋白偶联受体Smoothened (Smo)活性的抑制作用。

Recombinant Human Sonic Hedgehog expressed the target gene encoding Cys24-Gly197.


Accession: Q15465

Endotoxin < 0.01 EU/µg

Apparent Molecular Weight: 19 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, 1mM DTT, pH 7.5.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Haiying Zhou, et al. Mol Cell Biol. Mediator modulates Gli3-dependent Sonic hedgehog signaling

[2] V Marigo, et al. Nature. Biochemical evidence that patched is the Hedgehog receptor

100%好运必中
ChemBridge—化合物库中的金标准
  获取最新目录册
Abmole最新目录册
其他相关的Recombinant Proteins产品
Recombinant Human Serpin A12 (E.coli, N-GST)

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin is also a unique insulin sensitizing adipocytokine in obesity.

Recombinant Human B2M Protein (Mammalian, C-6His)

β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states.

Recombinant Mouse E-Selectin/CD62E Protein (HEK293)

E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involved in cancer cell metastasis.

Recombinant Human DPP4/CD26 (Mammalian, C-6His)

DPP4/CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family. DPP4/CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.

Recombinant Human USP14 (E.coli, N-6His)

USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1.





关键词:Recombinant Human Sonic Hedgehog/Shh (E.coli), SHH; HHG-1, Recombinant Human Sonic Hedgehog/Shh (E.coli)供应商, Recombinant Proteins抑制剂, 购买Recombinant Human Sonic Hedgehog/Shh (E.coli), Recombinant Human Sonic Hedgehog/Shh (E.coli)溶解度, Recombinant Human Sonic Hedgehog/Shh (E.coli)结构式








021-50967598      
2118621495      
inquiry@abmole.cn




产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。

Copyright © 2010-2022 AbMole版权所有    沪ICP备16047849号   沪公网安备 31011502012228号