R-spondin-1/RSPO1是一种分泌蛋白，含有2个FU（呋喃样）重复序列和1个TSP-1型结构域，属于R-spondin家族。重组人 R-spondin-1 由哺乳动物表达系统生产，目标基因编码为 Ser21-Ala263，C-末端带有 6His 标记。
R-spondin-1/RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. RSPO1 augments the WNT/β catenin pathway to oppose male sex development. RSPO1 can potentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. Recombinant Human R-spondin-1 is produced by Mammalian expression system, and the target gene encoding Ser21-Ala263 is expressed with a 6His tag at the C-terminus.
Measured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells, the ED50 for this effect is 4.06 ng/ml.
Accession: Q2MKA7
APMol Mass: 40 KDa, reducing conditions
Endotoxin < 0.01 EU/µg
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| 性状 | Lyophilized powder |
| 溶解性（25°C） | Dissolve the lyophilized protein in distilled water. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究