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Recombinant Human M-CSF (CHO) 重组人巨噬细胞群刺激因子(CHO)

目录号 M10592 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


Human M-CSF 蛋白 (CHO)是一种造血生长因子,具有多个糖基化位点,能够影响巨噬细胞的生存和功能,同时具有抗肿瘤活性。

Recombinant Human M-CSF (CHO)结构式

别名:Recombinant Human Macrophage Colony-stimulating Factor; CSF-1; rHM-CSF

规格 价格 库存状态
10ug ¥ 1980 中国库存现货
50ug ¥ 5040 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

Human M-CSF 蛋白 (CHO)是一种造血生长因子,具有多个糖基化位点,能够影响巨噬细胞的生存和功能,同时具有抗肿瘤活性。巨噬细胞集落刺激因子 (M-CSF),也称为集落刺激因子-1 (CSF-1),是一种造血生长因子。除了促进巨噬细胞的扩散和运动外,它还可以刺激单核吞噬细胞的存活、增殖和分化。M-CSF主要由单核细胞、巨噬细胞、成纤维细胞和内皮细胞产生。M-CSF 与其受体 c-fms 的相互作用与多种疾病的生长、侵袭和转移有关,包括乳腺癌和子宫内膜癌。

分子量:32~40 kDa

ED50 < 5.0 ng/ml, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 2.0 × 105 units/mg.

化学性质
溶解性(25°C) Reconstitute in ddH₂O or PBS up to 100 μg/ml
储存条件 Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Inmaculada Rioja, et al. Arthritis Rheum. Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor

[2] John A Hamilton. Nat Rev Immunol. Colony-stimulating factors in inflammation and autoimmunity

[3] M B Garnick, et al. Int J Cell Cloning. Preclinical and clinical evaluation of recombinant human macrophage colony-stimulating factor (rhM-CSF)

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