重组人白介素18(Recombinant Human IL-18)又被称之为γ-干扰素诱导因子,是一种炎性细胞因子,属于白介素1家族,可以由巨噬细胞和其他细胞产生。
别名:Interleukin18
重组人白介素18(Recombinant Human IL-18)又被称之为γ-干扰素诱导因子,是一种炎性细胞因子,属于白介素1家族,可以由巨噬细胞和其他细胞产生。IL-18和IL-12相结合能够产生抑制IL-4依赖的IgE和IgG1产生的作用,并且促进B细胞产生IgG2a。IL-18结合蛋白(IL-18BP)能特异性的与这种细胞因子相互作用,从而起到负向调节的生物活性。在体外实验中,IL-18和T细胞受体介导刺激能够诱导天然的CD4阳性T细胞进一步发展为IL-4产生的细胞。
在TNF-α存在的情况下,用KG-1产生IFN-γ的分泌量检测,ED50为 5~30 ng/mL。
分子量 ~18.2kD
内毒素 <0.1EU/ug
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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