重组人肝细胞生长因子 (rhHGF),也称为肝细胞生成素 A 和分散因子,是属于肽酶 S1 家族(纤溶酶原亚家族)的多效性有丝分裂原。它由间充质细胞产生,作用于上皮细胞、内皮细胞和造血祖细胞。
别名:rhHGF; Hepatocyte Growth Factor (HGF), Human
重组人肝细胞生长因子 (rhHGF),也称为肝细胞生成素 A 和分散因子,是属于肽酶 S1 家族(纤溶酶原亚家族)的多效性有丝分裂原。它由间充质细胞产生,作用于上皮细胞、内皮细胞和造血祖细胞。HGF 与原致癌 c-Met 受体结合以激活酪氨酸激酶信号级联。它调节细胞生长、运动和形态发生,因此在血管生成、肿瘤发生和组织再生中起关键作用。
ED50 < 10 ng/ml, measured in a cell proliferation assay using 4MBr5 cells, corresponding to a specific activity of > 1×105units/mg.
Accession: # P14210
Apparent Molecular Weight: 88~90 kDa (single chain), 59~61 kDa (alpha chain), 30~34 kDa (beta chain), on SDS-PAGE under reducing conditions.
Lyophilized after extensive dialysis against PBS.
溶解性(25°C) | Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. |
储存条件 | Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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