Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Sequence comparison of C1q from three different species have shown that the B chains have the strongest similarity. The recombinant human C1QB consists of 237 amino acids with the predicted molecular mass of 25.2 kDa.
别名:Complement Component 1, q subcomponent, B chain
补体成分 1,q 亚成分 (C1q) 与 C1r 和 C1s 结合以产生血清补体系统的第一个成分。C1q 缺乏与红斑狼疮和肾小球肾炎有关。C1q 由 18 条多肽链组成:6 条 A 链、6 条 B 链和 6 条 C 链。脊椎动物染色体 DNA 的 Southern 印迹分析表明 C1qB 基因之间的相似性最高,其次是 C1qC,最后是 C1qA。来自三个不同物种的C1q的序列比较表明B链具有最强的相似性。重组人 C1QB 蛋白由 237 个氨基酸组成,预测分子量为 25.2 kDa。表达了编码人 C1QB (NP_000482.3) 前体 (Met 1-Ala 253) 的 DNA 序列,带有羧基末端多组氨酸标签。
剂型描述:从无菌 50mM Tris、100mM NaCl、10% 甘油、0.5mM TCEP、pH 7.5 中冻干。
储存条件 | Stable for up to twelve months from date of receipt at -20℃ to -80℃ |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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