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Recombinant Human BMP-4 Protein (E. coli) 重组人BMP-4蛋白 (E. coli)

目录号 M31151 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


BMP-4 is involved in the development and maintenance of bone and cartilage. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells.

Recombinant Human BMP-4 Protein (E. coli)结构式

别名:Bone morphogenetic protein 4

规格 价格 库存状态
10ug ¥ 3150 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

BMP-4 is involved in the development and maintenance of bone and cartilage. Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells.


Accession: P12644

Molecular Weight: ~13.3 kDa

Endotoxin < 0.2 EU/μg

Lyophilized from a 0.2 μm filtered solution in 50 mM Na2CO3, 5 mM DTT, pH 11.0.

化学性质
性状 Lyophilized powder
溶解性(25°C) Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
储存条件 Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C.
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Jie Du, et al. J Orthop Translat. Intradiscal injection of human recombinant BMP-4 does not reverse intervertebral disc degeneration induced by nuclectomy in sheep

[2] Huabin Chen, et al. Ann Transl Med. Recombinant human bone morphogenetic protein-4 enhances tendon-to-bone attachment healing in a murine model of rotator cuff tear

[3] Che Lin Kim, et al. Metab Eng. Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines

[4] Maksim V Plikus, et al. Science. Regeneration of fat cells from myofibroblasts during wound healing

[5] Matija Rojnik, et al. Radiol Oncol. Cathepsin H indirectly regulates morphogenetic protein-4 (BMP-4) in various human cell lines

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