重组人DKK-1蛋白 (Mammalian, N-8His) 由哺乳动物表达系统产生，编码Thr32-His266的目的基因在N端以8His标记表达。Accession #: O94907。
别名：Dickkopf-related protein 1;Dickkopf-1;Dkk-1
纯度：还原SDS-PAGE测定大于95%。
内毒素:LAL测定:小于0.001 ng/ug (0.01 EU/ug)。
保存：冻干蛋白应在< -20°C保存，但在室温下可保存3周。重组蛋白溶液可在4-7℃下保存2-7天。重组样品的等分液在< -20°C下稳定3个月。
生物活性：dickkopf相关蛋白1(dickkopf -related protein 1, DKK-1)是dickkopf家族的成员。DKK1分泌的蛋白质有两个富含半胱氨酸的区域，由连接区隔开。它通过抑制LRP5/6与Wnt的相互作用以及与跨膜蛋白KREMEN形成促进LRP5/6内化的三元复合物来对抗典型的Wnt信号。在成人中，Dkks与骨形成和骨病、癌症和阿尔茨海默病有关。
| 溶解性（25°C） | It is not recommended to reconstitute to a concentration less than 100 μg/ml. |
| 储存条件 | -20°C |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究