RNA Synthesis IN-1  别名：RNA合成抑制剂1

Oncogene. 2025 Dec 08; .

circSETD3 confers radiotherapy resistance in nasopharyngeal carcinoma by attenuating ER stress-induced autophagy and apoptosis via PDIA6 upregulation.

Oncogene. 2025 May 26; .

m6A modification-dependent upregulation of WNT2 facilitates M2-like macrophage polarization and perpetuates malignant progression of nasopharyngeal carcinoma

J Med Virol. 2025 Apr 29;97(5):e70356.

Hepatitis B Virus Promotes Angiogenesis in Hepatocellular Carcinoma by Increasing m6A Modification of VEGFA mRNA via IGF2BP3

Clin Transl Med. 2025 Sep 26;15(10):e70483.

Radiation-induced extracellular vesicles from cancer-associated fibroblasts drive oesophageal squamous cell carcinoma metastasis via the miR-193a-3p/PTEN/Akt pathway

Analytical Chemistry. 2025 Dec 03;Vol 97:Issue 49.

Spatial Mapping and Interactome Profiling of m6A-Modified R-Loops via Chemically Inducible Split-APEX2 Proximity Labeling

Cell Death Discov. 2025 Mar 13;11(1):101.

m6A-modified LINC02418 induces transcriptional and post-transcriptional modification of CTNNB1 via interacting with YBX1 and IGF2BP1 in colorectal cancer

Mol Med. 2025 Jan 24;31(1):24.

Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis

J Ethnopharmacol. 2025 Nov 27;357:120948.

Qiteng Xiaozhuo Granules improve chronic glomerulonephritis through promoting glomerular mesangial cell autophagy via FTO-mediated SLC7A5 m6A modification.

Biochem Pharmacol. 2025 Jun;236:116867.

Inhibition of METTL3 promotes mesangial cell mitophagy and attenuates glomerular damage by alleviating FOSL1 m6A modifications via IGF2BP2-dependent mechanisms

Cell Signal. 2025 Mar;127:111533.

tRNA methyltransferase DNMT2 promotes hepatocellular carcinoma progression and enhances Bortezomib resistance through inhibiting TNFSF10

Biochim Biophys Acta Mol Basis Dis. 2025 Dec 01;1872:168129.

H3K9 lactylation drives FTO-mediated NRF2 suppression to exacerbate bladder epithelial ferroptosis and inflammation in diabetic bladder dysfunction.

J Inflamm Res. 2025 Aug 24;18:11577-11592.

NRF2 Deficiency in Bladder Epithelial Cells Owing to Ubiquitination by N6-Methyladenosine-Modified TRIM21 Induces Oxidative Stress and Inflammation to Aggravate IC/BPS

Sci Rep. 2025 Dec 18; .

METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial-mesenchymal transition.

Exp Cell Res. 2025 Jun 10; .

LncRNA USP2-AS1 Facilitates Colorectal Cancer Development Through The PHLDA2/PI3K/AKT Axis

Hum Cell. 2025 Feb 26;38(2):62.

MTHFD2 stabilizes LOX expression through RNA methylation modification to promote sepsis-induced acute kidney injury progression

BMC Cancer. 2025 May 30;25(1):970.

NAT10 inhibits the pyroptosis of laryngeal squamous cell carcinoma through ac4C modification of ELANE mRNA

Kaohsiung J Med Sci. 2025 Sep 27; .

Human Breast Milk‐Derived Exosomal FP671120. 4 Inhibits Macrophage M1 Polarization via Modulating the ELAVL1/Nrf2 Axis in Sepsis‐Associated Liver Injury

Immunol Res. 2025 Oct 15;73(1):145.

METTL14 aggravates pyroptosis in diabetic cardiomyopathy by promoting m6A modification of NLRP3

Int J Biochem Cell Biol. 2025 Jun 15; .

METTL5-mediated m6A modification of SLC7A11 promotes cervical cancer by inhibiting ferroptosis

Brain Res. 2025 Feb 01;1872:150088.

ZFP36 attenuates neuronal apoptosis and pyroptosis through inhibiting TXNIP/NLRP3 pathway in hypoxic-ischemic brain damage.

Biochem Biophys Res Commun. 2025 Apr 09;763:151770.

The Role of JPX in Regulating FUS/SLC7A11 Signaling Pathway Mediated Ferroptosis in Keloid Fibroblasts and its Potential in Scar Repair

Adv Sci (Weinh). 2024 Jan;e2207435.

Defective Homologous Recombination Repair By Up-Regulating Lnc-HZ10/Ahr Loop in Human Trophoblast Cells Induced Miscarriage

Adv Sci (Weinh). 2024 Sep 04;e2401118.

CRISPR/dCas13(Rx) Derived RNA N6-methyladenosine (m6A) Dynamic Modification in Plant

Exp Mol Med. 2024 Mar 1.

RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer

Exp Mol Med. 2024 Jun 3.

METTL3-mediated pre-miR-665/DLX3 m6A methylation facilitates the committed differentiation of stem cells from apical papilla

J Exp Clin Cancer Res. 2024 Jun 20;471:134331.

ALKBH5 promotes non-small cell lung cancer progression and susceptibility to anti-PD-L1 therapy by modulating interactions between tumor and macrophages

Cancer Lett. 2024 Jun 3;596:217004.

m6A modification of lncRNA ABHD11-AS1 promotes colorectal cancer progression and inhibits ferroptosis through TRIM21/IGF2BP2/ FOXM1 positive feedback loop

Cancer Letters. 2024 Jun 22;16(1):2334967.

NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization

Pharmacol Res. 2024 Dec 01;210:107509.

METTL14-mediated m6A modification enhances USP22-ERα axis to drive breast cancer malignancy

Cell Death Dis. 2024 Jan;13;15(1):43.

METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner

Cell Death Dis. 2024 Mar 11;15(3):205.

GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas

Cell Death Dis. 2024 Mar 20;15(3):229.

METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway

Cell Mol Life Sci. 2024 Jun 9;81(1):253.

Poly (ADP-ribose) polymerase 1 promotes HuR/ELAVL1 cytoplasmic localization and inflammatory gene expression by regulating p38 MAPK activity

Int J Biol Macromol. 2024 Oct 30.

Circular RNA circWBSCR22 facilitates colorectal cancer metastasis by enhancing CHD4's protein stability

Free Radic Biol Med. 2024 Aug 23;224:130-143.

Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation

Oncogene. 2024 Oct 10.

m6A-driven NAT10 translation facilitates fatty acid metabolic rewiring to suppress ferroptosis and promote ovarian tumorigenesis through enhancing ACOT7 mRNA acetylation

Plant Physiol. 2024 Aug 07.

N6-methyladenosine RNA modification regulates photoperiod sensitivity in cotton

Virus Res. 2024 Jan 2;339:199273.

Gambogic acid inhibits HBx-mediated hepatitis B virus replication by targeting the DTX1-Notch signaling pathway

Cell Mol Life Sci. 2024 Jun 16.

Poly (ADP-ribose) polymerase 1 promotes HuR/ELAVL1 cytoplasmic localization and inflammatory gene expression by regulating p38 MAPK activity

J Nutr Biochem. 2024 Jan;3:125:109563.

Dietary selenomethionine reduced oxidative stress by resisting METTL3-mediated m6A methylation level of Nrf2 to ameliorate LPS-induced liver necroptosis in laying hens

Cancer Cell Int. 2024 Sep 19;24(1):321.

The role of KRT7 in metastasis and prognosis of pancreatic cancer

J Biol Chem. 2024 Mar 25;300(5):107226.

Epstein-Barr virus suppresses N6-Methyladenosine modification of TLR9 to promote immune evasion

Scientific Reports. 2024 Jan ;9;14(1):904.

Hsa_circ_0081065 exacerbates IH-induced EndMT via regulating miR-665/HIF-1α signal axis and HIF-1α nuclear translocation

J Gastroenterol Hepatol. 2024 Oct 15.

The m6A reader IGF2BP1 contributes to the activation of hepatic stellate cells through facilitating TUBB4B mRNA stabilization

Plant Growth Regulation. 2024 Aug 04.

Dissecting the roles of increased mRNA m6A methylation in autotetraploidization in Stevia rebaudiana

Hum Mol Genet. 2024 Aug 31.

TRIM25 activates Wnt/β-catenin signalling by destabilising MAT2A mRNA to drive thoracic aortic aneurysm development

Mol Carcinog. 2024 Aug 02.

m6A modification of VEGFA mRNA by RBM15/YTHDF2/IGF2BP3 contributes to angiogenesis of hepatocellular carcinoma

Gene. 2024 Oct 01.

NIPSNAP3A regulates cellular homeostasis by modulating mitochondrial dynamics

Patent. CN118064581A 2024 May 24.

Patent. CN118064581A

Adv Sci (Weinh). 2023 Jan;10(2):e2201724.

Silencing of IRF8 Mediated by m6A Modification Promotes the Progression of T‐Cell Acute Lymphoblastic Leukemia

J Hazard Mater. 2023 May 6;455:131543.

BPDE exposure promotes trophoblast cell pyroptosis and induces miscarriage by up-regulating lnc-HZ14/ZBP1/NLRP3 axis

Plant Biotechnol J. 2023 Mar 22.

N6‐methyladenosine RNA modification regulates cotton drought response in a Ca2+ and ABA‐dependent manner

J Exp Clin Cancer Res. 2023 May 19;42(1):127.

Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1

Plant Cell. 2023 Jun 27;koad189.

N4-acetylation of cytidine in (m) RNA plays essential roles in plants

Int J Biol Sci. 2023 Jan 1;19(2):691-704.

Upregulation of LRRC8A by m5C modification-mediated mRNA stability suppresses apoptosis and facilitates tumorigenesis in cervical cancer

Antiviral Res. 2023 Jan;209:105482.

Ciliatoside A, isolated from Peristrophe japonica, inhibits HBsAg expression and cccDNA transcription by inducing autophagy

Sci Total Environ. 2023 Sep 18;167202.

m6A methylation-mediated PGC-1α contributes to ferroptosis via regulating GSTK1 in arsenic-induced hepatic insulin resistance

Cell Death Dis. 2023 Sep 21;14(9):619.

Interfering with Rac1-activation during neonatal monocyte-macrophage differentiation influences the inflammatory responses of M1 macrophages

Front Immunol. 2023 Mar 30;14:1144774.

LRPPRC facilitates tumor progression and immune evasion through upregulation of m6A modification of PD-L1 mRNA in hepatocellular carcinoma

J Transl Med. 2023 Jun 23;21(1):407.

METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing

Oncogene. 2023 Nov 7.

Low expression of ZFP36L1 in osteosarcoma promotes lung metastasis by inhibiting the SDC4-TGF-β signaling feedback loop

Biomed Pharmacother. 2023 May;161:114575.

Targeting the TNF-α–TNFR interaction with EGCG to block NF-κB signaling in human synovial fibroblasts

Clin Epigenetics. 2023 Jul 5;15(1):109.

FTO-dependent m6A regulates muscle fiber remodeling in an NFATC1–YTHDF2 dependent manner

Cell Biol Toxicol. 2023 Oct;39(5):2165-2181.

AS3MT facilitates NLRP3 inflammasome activation by m6A modification during arsenic-induced hepatic insulin resistance

Clin Epigenetics. 2023 Jul 5;15(1):109.

FTO-dependent m6A regulates muscle fiber remodeling in an NFATC1-YTHDF2 dependent manner

J Cell Biochem. 2023 Feb;124(2):239-253.

IGF2BP2 enhances LincRNA01116 stability via m6A: A potential biomarker and therapeutic target for patients with pre‐eclampsia

Mol Biomed. 2023 Nov 17;4(1):42.

Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma

BMC Complementary Medicine and Therapies. 2023 Jul 1.

NAT10-mediated RNA acetylation enhances HNRNPUL1 mRNA stability to contribute cervical cancer progression

J Orthop Sci. 2023 May 27;S0949-2658(23)00133-1.

CircBBS9 accelerates the malignant progression of osteosarcoma through sponging miR-485-3p/HMGB1 axis

BioRxiv. 2023 Sep 04;556177.

Stabilization of RRBP1 mRNA via an m6A-dependent manner in prostate cancer constitutes a therapeutic vulnerability amenable to small-peptide inhibition of METTL3

BioRxiv. 2023 Jan 28;526069.

m6A Demethylase FTO Stabilizes LINK-A to Exert Oncogenic Roles via MCM3-Mediated Cell Cycle Progression and HIF-1α Activation

Mol Cancer. 2022 Feb 14;21(1):49.

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction

Cells. 2022 Sep 27;11(19):3008.

m6A Modification of Long Non-Coding RNA HNF1A-AS1 Facilitates Cell Cycle Progression in Colorectal Cancer via IGF2BP2-Mediated CCND1 mRNA Stabilization

Cell Biol Toxicol. 2022 Feb 28;1-17.

AS3MT facilitates NLRP3 inflammasome activation by m6A modification during arsenic-induced hepatic insulin resistance

iScience. 2022 Nov 10;25(12):105552.

Chromodomain helicase DNA-binding domain 2 maintains spermatogonial self-renewal by promoting chromatin accessibility and mRNA stability

Molecules. 2022 May 16;27(10):3182.

A Novel Strategy for Regulating mRNA's Degradation via Interfering the AUF1's Binding to mRNA

Cancer Lett. 2021 Dec 28;523:135-147.

IGFBP7-AS1 is a p53-responsive long noncoding RNA downregulated by Epstein-Barr virus that contributes to viral tumorigenesis

Theranostics. 2020 Apr 27;10(13):5671-5686.

SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma