Recombinant Mouse Interleukin-4是一种多效性细胞因子，可调节多种T和B细胞反应，包括细胞增殖、存活和基因表达。IL-4 调节天然 CD4+ T 细胞（Th0 细胞）向辅助 Th2 细胞的分化，并调节免疫球蛋白类别转换为 IgG1 和 IgE 同种型。
Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. It is produced by mast cells, activated T cells and bone marrow stromal cells. IL-4 regulates the differentiation of native CD4+ T cells (Th0 cells) into helper Th2 cells, and regulates the immunoglobulin class switching to the IgG1 and IgE isotypes. IL-4 also plays a major role in inflammation response and wound repair via activation of macrophage into M2 cells.
Measured in a cell proliferation assay using M-NFS-60 mouse lymphoblast cells, the ED50 for this effect is 0.01 ng/ml.
Accession: P07750
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 14 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, 5% Trehalose, pH 6.5.
| 性状 | Lyophilized powder |
| 溶解性（25°C） | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| 储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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蛋白质研究