Protein Synthesis IN-1  别名：蛋白质合成抑制剂1

Antioxid Redox Signal. 2025 Sep 26; .

Empagliflozin Attenuates Diabetic Cardiomyopathy via Inhibiting Cardiomyocyte Ferroptosis Through the USP7/NRF2 Signaling Pathway

Chem Biol Interact. 2025 Aug 06; .

Cigarette smoke-induced glycerophospholipid DLPC promotes macrophage ferroptosis through the USP7/GPX4 regulatory axis in chronic obstructive pulmonary disease

Commun Biol. 2025 Dec 03; .

Structure guided analysis of KRAS G12 mutants in HLA-A*11:01 reveals a length encoded immunogenic advantage in G12D.

Int Immunopharmacol. 2025 Jan 10;144:113564.

ITGB4/GNB5 axis promotes M2 macrophage reprogramming in NSCLC metastasis

J Virol. 2025 Jan 31;99(1):e0127724.

Swine RNF5 positively regulates the antiviral activity of IFITM1 by mediating the degradation of ABHD16A

J Pharm Sci. 2025 Jul 08; .

Impact of droplet size and surface charge on oral bioavailability of Norcantharidin-loaded SEDDS: Mechanistic insights into lymphatic transport and intestinal permeability

Mol Biol Rep. 2025 Jun 24;52(1):633.

UBE3C promotes pancreatic ductal adenocarcinoma progression by catalysing p53 ubiquitination

Mol Cancer. 2024 Dec 19;23(1):274.

ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis

Adv Sci (Weinh). 2024 Jan;e2207435.

Defective Homologous Recombination Repair By Up-Regulating Lnc-HZ10/Ahr Loop in Human Trophoblast Cells Induced Miscarriage

Autophagy. 2024 Jun 6.

The novel lnc-HZ12 suppresses autophagy degradation of BBC3 by preventing its interactions with HSPA8 to induce trophoblast cell apoptosis

Brain. 2024 Jun 25.

Heterozygous variants in USP25 cause genetic generalized epilepsy

Environ Int. 2024 Sep;191:108975.

BaP/BPDE suppresses homologous recombination repair in human trophoblast cells to induce miscarriage: The roles of lnc-HZ08

Cancer Lett. 2024 Apr 6;590:216861.

TRAF6 enhances PD-L1 expression through YAP1-TFCP2 signaling in melanoma

Free Radic Biol Med. 2024 Aug 23;224:130-143.

Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation

iScience. 2024 May 15.

Deficiency in Prader-Willi syndrome gene necdin leads to attenuated cardiac contractility

PLoS Pathog. 2024 Sep 30;20(9):e1012594.

TRIM56 restricts Coxsackievirus B infection by mediating the ubiquitination of viral RNA-dependent RNA polymerase 3D

J Biol Chem. 2024 Mar 25;300(5):107226.

Epstein-Barr virus suppresses N6-Methyladenosine modification of TLR9 to promote immune evasion

Cell Signal. 2024 May 26;111235.

BMSC derived EVs inhibit colorectal Cancer progression by transporting MAGI2-AS3 or something similar

Respir Res. 2024 Jul 25;25(1):287.

Novel hypoxia-induced HIF-1αactivation in asthma pathogenesis

Mol Carcinog. 2024 Jan.

SN-38, an active metabolite of irinotecan, inhibits transcription of nuclear factor erythroid 2-related factor 2 and enhances drug sensitivity of colorectal cancer cells

iScience. 2024 Jan 19.

FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression

Mol Cell Biochem. 2024 Feb 17.

Tripartite-motif 3 represses ovarian cancer progression by downregulating lactate dehydrogenase A and inhibiting AKT signaling

Sci Rep. 2024 Oct 10;14(1):23685.

USP10 promotes cell proliferation, migration, and invasion in NSCLC through deubiquitination and stabilization of EIF4G1

Viruses. 2024 Sep 23;16(9):1503.

N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1

Leuk Res. 2024 Jun 29;52(1):46.

Combining the novel FLT3 and MERTK dual inhibitor MRX-2843 with venetoclax results in promising antileukemic activity against FLT3-ITD AML

BioRxiv. 2024 Feb 10;579754.

Clearance of protein aggregates during cell division

Patent. CN117535410A 2024 Feb 09.

Patent. CN117535410A

J Transl Med. 2023 May 5;21(1):303.

SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion

Cell Death Discov. 2023 Apr 26.

Ammonium Tetrathiomolybdate Relieves Oxidative Stress in Cisplatin-induced Acute Kidney Injury via NRF2 Signaling Pathway

Cell Death Discov. 2023 Jul 25;9(1):259.

Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway

J Cell Mol Med. 2023 Aug 29.

Alleviation of temporomandibular joint osteoarthritis by targeting RIPK1-mediated inflammatory signalling

FASEB J. 2023 Oct;37(10):e23183.

IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner

New Journal of Chemistry. 2023 Jun 20.

Quantitative analysis of the effects of vimentin intermediate filaments on the early stages of influenza A virus infection

New J. Chem. 2023 Jun 28;47, 14344-14354.

Quantitative analysis of the effects of vimentin intermediate filaments on the early stages of influenza A virus infection

Biochem Genet. 2023 Nov 11.

Functional Characterization of a Novel SLC4A4 Variant and Uniparental Isodisomy in Proximal Renal Tubular Acidosis Patient

Cell Death Differ. 2022 Jul;29(7):1395-1408.

SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK

Research Square. 2022 Oct 12.

IGF2BP2 promotes ovarian cancer growth and metastasis via upregulating CKAP2L protein expression in a m6A-dependent manner

Ecotoxicol Environ Saf. 2022 Jun 1;237:113564.

Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop

Virol Sin. 2022 Aug 16;S1995-820X(22)00143-2.

CK1α upregulates the IFNAR1 expression to prompt the anti-HBV effect of type I IFN in hepatoma carcinoma cells

Cell Biol Toxicol. 2022 Apr;38(2):291-310.

Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage

Bioengineered. 2022 Apr;13(4):8000-8012.

UBE2B promotes ovarian cancer growth via promoting RAD18 mediated ZMYM2 monoubiquitination and stabilization

J Biol Chem. 2022 Nov 21;102734.

Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer

Mol Cell Endocrinol. 2022 Apr 5;545:111575.

An intron mutation of HNF1A causes abnormal splicing and impairs its activity as a transcription factor

Adv Sci (Weinh). 2021 Feb.

Inhibition Lysosomal Degradation of Clusterin by Protein Kinase D3 Promotes Triple‐Negative Breast Cancer Tumor Growth

Adv Sci (Weinh). 2021 Jan 6;8(4):2003205.

Inhibition Lysosomal Degradation of Clusterin by Protein Kinase D3 Promotes Triple-Negative Breast Cancer Tumor Growth

Clin Transl Med. 2021 Apr;11(4):e395.

FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression

Int J Mol Sci. 2021 Aug 16;22(16):8779.

Autophagy Mediates the Degradation of Plant ESCRT Component FREE1 in Response to Iron Deficiency

J Cancer. 2021 Oct 17;12(23):7041-7051.

N6-methyladenosine regulates ATM expression and downstream signaling

Cell Rep. 2020 Jul 28;32(4):107974.

L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis

Cell Rep. 2020 Jul 28;32(4):107974.

LARP7 is a BRCA1 ubiquitinase substrate and regulates genome stability and tumorigenesis

Theranostics. 2020 Apr 27;10(13):5671-5686.

SUMO1 modification of methyltransferase-like 3 promotes tumor progression via regulating Snail mRNA homeostasis in hepatocellular carcinoma

Cell Oncol (Dordr). 2020 Oct 19.

Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A

Cell Microbiol. 2020 Mar;22(3):e13148.

Hepatitis B virus X protein modulates upregulation of DHX9 to promote viral DNA replication.

Life Sci. 2020 Sep 15;257:118021.

TRIB3 destabilizes tumor suppressor PPARα expression through ubiquitin-mediated proteasome degradation in acute myeloid leukemia

Front Cell Infect Microbiol. 2020 Apr 16;10:158.

Difluoromethylornithine, a Decarboxylase 1 Inhibitor, Suppresses Hepatitis B Virus Replication by Reducing HBc Protein Levels

BioRxiv. 2019; .

LARP7 is a BRCA1 ubiquitinase substrate and regulates genome stability and tumorigenesis

Aging (Albany NY). 2018 Oct 18;10(10):2783-2799.

Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-β signaling-induced epithelial-mesenchymal transition.

Biotechnol Lett. 2018 Aug;40:1181-1188.

UHRF2 promotes DNA damage response by decreasing p21 via RING finger domain.

Protein Cell. 2017 Mar;8(3):202-218.

E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain