重组人TNF-α蛋白是一个同源三聚体，其亚单位分子质量为17.3 kDa。TNF-a在生长调节、分化、炎症、病毒复制、肿瘤发生和自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中发挥着重要作用。
别名：TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin
重组人TNF-α蛋白是一个同源三聚体，其亚单位分子质量为17.3 kDa。TNF-a在生长调节、分化、炎症、病毒复制、肿瘤发生和自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中发挥着重要作用。
在有代谢抑制剂放线菌素D的情况下，用L-929小鼠纤维肉瘤细胞进行细胞毒性测定的ED50 < 30.0 pg/ml，对应的比活性为>3.3 × 107 units/mg。
蛋白编号： # P01375
表观分子量：~17.3 kDa，还原条件下SDS-PAGE。
剂型描述：从 0.2 μm 过滤的 PBS 溶液中冻干。
| 溶解性（25°C） | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| 储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
[1] Elissavet Kemanetzoglou, et al. Curr Neurol Neurosci Rep. CNS Demyelination with TNF-α Blockers
[2] Helga Radner, et al. Wien Med Wochenschr. Anti-TNF in rheumatoid arthritis: an overview
[3] T Tzanavari, et al. Curr Dir Autoimmun. TNF-alpha and obesity
[4] Frances Balkwill. Cancer Metastasis Rev. TNF-alpha in promotion and progression of cancer
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蛋白质研究