TNF-α是由脂肪细胞、活化的单核细胞、巨噬细胞、B 细胞、T 细胞和成纤维细胞等多种细胞分泌的多效性促炎细胞因子。
别名:TNFSF2
TNF-α是由脂肪细胞、活化的单核细胞、巨噬细胞、B 细胞、T 细胞和成纤维细胞等多种细胞分泌的多效性促炎细胞因子。TNF-α对多种肿瘤细胞具有细胞毒性,是介导细菌感染免疫应答的重要因子。TNF-α在感染性休克、自身免疫性疾病、类风湿性关节炎、炎症和糖尿病的诱导中也发挥作用。
通过使用L-929小鼠纤维肉瘤细胞的细胞毒性试验中测得的ED50为 <0.05 ng/ml,对应的比活力为 >2.0 × 107 units/mg。
蛋白编号:P06804
表观分子量:~17.3 kDa
内毒素 < 0.2 EU/μg
剂型描述:从0.2 μm过滤的PBS溶液中冻干。
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
储存条件 | Stable for up to 6 months at ≤ -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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