重组小鼠M-CSF (HEK 293) 蛋白是由淋巴细胞、单核细胞、成纤维细胞、内皮细胞、成肌细胞和成骨细胞等多种细胞产生的一种强大的造血因子和促炎细胞因子,能与其受体CSF1R结合,参与单核细胞/巨噬细胞谱系细胞的发育和增殖,以及参与破骨细胞的诱导。
别名:CSF-1; MGI-IM
重组小鼠M-CSF蛋白 (HEK 293)是由淋巴细胞、单核细胞、成纤维细胞、内皮细胞、成肌细胞和成骨细胞等多种细胞产生的一种强大的造血因子。M-CSF在调节真皮厚度和生育力方面发挥着重要作用。M-CSF应用于感染、恶性肿瘤和动脉粥样硬化,促进骨髓移植后造血功能的恢复。
按剂量依赖性刺激M-NFS-60细胞增殖的ED50为≤1.0 ng/ml,对应的比活性≥1×106 IU/mg。
DNA 序列编码小鼠 M-CSF(NP_031804.3)表达带有 His 标签在 C 末端。
重组小鼠 M-CSF蛋白包含 161 个氨基酸,预测理论分子量为 18.9kD。
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100μg/mL |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Upon reconstitution, the product should be stable for up to 6 months at -20°C. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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