Recombinant Mouse Interleukin-4是一种多效性细胞因子,可调节多种T和B细胞反应,包括细胞增殖、存活和基因表达。IL-4 调节天然 CD4+ T 细胞(Th0 细胞)向辅助 Th2 细胞的分化,并调节免疫球蛋白类别转换为 IgG1 和 IgE 同种型。
别名:rMuIL-4
Recombinant Mouse Interleukin-4 is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. It is produced by mast cells, activated T cells and bone marrow stromal cells. IL-4 regulates the differentiation of native CD4+ T cells (Th0 cells) into helper Th2 cells, and regulates the immunoglobulin class switching to the IgG1 and IgE isotypes. IL-4 also plays a major role in inflammation response and wound repair via activation of macrophage into M2 cells.
ED50 < 2 ng/ml, measured in a cell proliferation assay using murine HT-2 cells, corresponding to a specific activity of >5 x 105 units/mg.
Accession: # P07750
Apparent Molecular Weight: ~15 kDa, on SDS-PAGE under reducing conditions.
Lyophilized after extensive dialysis against PBS.
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
储存条件 | Stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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