Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。
Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子。VEGF 促进内皮细胞的增殖和存活,促进血管生成和血管通透性。VEGF 在血管化组织中表达,在正常和病理血管生成中起着重要作用。大量证据表明 VEGF 在诱导肿瘤转移和眼内新生血管综合征中有重要作用。VEGF 通过 FMS-like 酪氨酸激酶(Flt-1)、KDR 基因产物(小鼠同源性为 FLK--1 基因产物)和 FLT 4 基因产物表达。
DNA 序列编码人 VEGF165(NP_001165097.1)表达带有 His 标签在 C 末端。
重组人 VEGF165 包含 193 个氨基酸,预测的理论分子量为 22.3kd。
通过用人脐静脉内皮细胞(HUVEC)进行细胞增殖测定,该效应的ED50为≤20 ng/mL。
Endotoxin <0.1EU/μg
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USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma
Sci Rep. 2019 Nov 28;9(1):17745.
In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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