重组人白介素21（Recombinant Human IL-21）是一种由应答抗原刺激CD4+ T细胞产生的多效性细胞因子，能提高免疫细胞的抗原特异性反应。
别名：Interleukin 21、rhIL-21
重组人白介素21（Recombinant Human IL-21）是一种由应答抗原刺激CD4+ T细胞产生的多效性细胞因子，能提高免疫细胞的抗原特异性反应。IL-21 由活化的 T 滤泡辅助细胞（tfh）、Th17 细胞和 NKT 细胞产生。T 滤泡辅助细胞衍生的 IL-21 在通过其对 T 滤泡辅助细胞的自分泌作用和对免疫球蛋白亲和成熟、血浆细胞的旁分泌作用发展体液免疫分化和 B 细胞记忆反应，而树突状细胞迁移到引流淋巴结也是必需的。IL-21 能够调节 T 细胞多方面的功能:共同刺激 CD8 的活化、增殖和存活。
此外，IL-21 抑制皮肤过敏的作用是通过限制过敏原特异性 IgE 产生和肥大细胞脱粒的反应。IL-21/IL-21R 结合后激活酪氨酸激酶 JAK1 和 JAK3，随后转录因子 STAT1 和 STAT3 活化。
内毒素（Endotoxin）<2EU/mg
| 溶解性（25°C） | Water Saline PBS |
| 储存条件 | 2-8°C, dry, protect from light, sealed |
| 运输方式 | 冰袋运输，根据产品的不同，可能会有相应调整。 |
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