重组人白介素2(Recombinant Human IL-2)可以使活化的T细胞在体外培养中长期持续增殖。
别名:IL2; Interleukin-2
重组人白介素2(Recombinant Human IL-2)可以使活化的T细胞在体外培养中长期持续增殖。静止的T细胞表面不表达IL-2R,对IL-2没有反应;受丝裂原或其它刺激活化后T细胞才能表达IL-2R,成为IL-2的靶细胞。NK细胞是唯一正常情况下表达IL-2R的淋巴样细胞,因此始终对IL-2保持反应性。然而静止的NK细胞上只表达IL-2R的β链和γ链,对IL-2的亲和力低,只能对高浓度的IL-2发生反应。一旦NK细胞活化,就表达IL-2R的α链,成为高亲和力的受体。
通过用 CTLL-2 细胞进行细胞增殖测定,该效应的生物学活性为 2×107IU/mg。
预测的理论分子量为 15.4kD
Endotoxin < 0.1 EU/μg
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS to 100 μg/ml. |
储存条件 | Stored at ≤-20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
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