白介素 1 (IL-1)是一种多肽,分子质量为17 kd,有IL-1α及IL-1β两种亚型。IL-1ɑ由159个氨基酸组成。
白介素 1 (IL-1)是一种多肽,分子质量为17 kd,有IL-1α及IL-1β两种亚型。IL-1ɑ由159个氨基酸组成。IL-1 受体(IL-1R)几乎存在于所有有核细胞表面,每个细胞的 IL-1R 数目不等,少则几十个(如 t 细胞),多则数千个(如成纤维细胞)。IL-1R 主要有两种类型:一种为 IL-1r1,其分子伸入胞浆内的肽链部分较长,起着传递活化信号的作用;另一种为 IL-1R2,胞内部分的肽段较短不能有效地传递信号,而是将胞外部分的肽链释放到细胞外液中,以游离形式与 IL-1 结合,发挥反馈抑制作用。GM-CSF、G-CSF及 IL-1 自身均可提高细胞 IL-1R 的表达水平,而 TGF 及皮质类固醇能降低 IL-1R 的表达。
通过其诱导人自然杀伤性淋巴瘤 NK-92 细胞分泌干扰素γ 的能力测定,该效应的ED50为 ≤100 ng/mL。
内毒素 <0.1EU/ug
性状 | Lyophilized powder |
溶解性(25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
储存条件 | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
运输方式 | 冰袋运输,根据产品的不同,可能会有相应调整。 |
其他相关的Recombinant Proteins产品 |
---|
Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
Recombinant Human EpCAM/Trop-1 (Mammalian, C-Fc)
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein. EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells. |
Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli, aa 18-169, His Tag)
The recombinant human IL1F9 consists of 168 amino acids and predicts a molecular mass of 19.1 KDa. A DNA sequence encoding the mature form of human IL1F9 (Ser18-Asp169) was expressed with a polyhistide tag at the N-terminus. |
Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli)
The recombinant human IL1F9 consisting of 169 amino acids and has a calculated molecular mass of 18.9 kDa. A DNA sequence encoding the human IL-1F9 isoform 1 (Met 1-Asp 169) was expressed. |
Recombinant Human APOL1 Protein (Baculovirus-Insect, C-His)
APOL1, also known as apolipoprotein L1, belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. |
产品仅供科学研究或药证申报的用途使用,不为任何个人或者非科研性质的其他用途提供服务。
Copyright © 2010-2022 AbMole版权所有 沪ICP备16047849号 沪公网安备 31011502012228号