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FGF-basic, Rat (E. coli)

目录号 M11496 所有产品仅供科研使用,严禁用于人或动物的治疗等任何其他用途,不为任何个人提供产品和服务  


FGF-basic, Rat(E. coli) 蛋白构造:Expressed with an N-terminal Gly.FGF-basic (Pro10-Ser154) Accession # P13109。 生物活性:ED50 < 0.25 ng/ml,采用3T3细胞增殖法测定,对应> 4.0 × 106单位/mg。

FGF-basic, Rat (E. coli)结构式

别名:Fibroblast Growth Factor-basic; FGF-2; BFGF; FGFB; HBGF-2; bFGF; Prostatropin

规格 价格 库存状态
10ug ¥ 1170 中国库存现货
50ug ¥ 2070 中国库存现货
其他规格数量报价?

质量标准及产品资料
  • 纯度: >95% , Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
生物活性

表达系统:E. coli

纯度:SDS-PAGE分析> 95%

内毒素:凝胶凝血法测定蛋白质< 0.2 EU/μg

表观分子量:~16.4 kDa,在SDS-PAGE还原条件下。

存储及稳定性:在接收后,该产品在低于-70°C的环境下保持稳定长达6个月。重组后,产品应在4°C下稳定1周或在-20°C下稳定3个月。为了长期保存,建议添加载体蛋白(如0.1% BSA)。避免反复的冻融循环。


生物活性:碱性成纤维细胞生长因子(FGF-basic)(E. coli),也被称为FGF-2,是一种多效细胞因子,也是肝素结合FGF家族的原型成员之一。与其他FGF家族成员一样,碱性FGF具有β三叶结构。在体内,碱性成纤维生长因子由多种细胞产生,包括心肌菌群、成纤维细胞和血管细胞。碱性成纤维生长因子调节多种过程,包括细胞增殖、分化、存活、粘附、运动、凋亡、肢体形成和伤口愈合。

化学性质
溶解性(25°C) Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml.
储存条件 粉末型式       -20°C   3年;4°C   2年
溶于溶剂       -80°C   6个月;-20°C   1个月
运输方式 冰袋运输,根据产品的不同,可能会有相应调整。
参考文献

[1] Yong Li, et al. J Cardiovasc Pharmacol. Effect of NRG-1/ErbB signaling intervention on the differentiation of bone marrow stromal cells into sinus node-like cells

[2] F Marn, et al. J Pineal Res. Immunocytochemical localization of basic fibroblast growth factor in the rat pineal gland

[3] A U Dignass, et al. Gastroenterology. Fibroblast growth factors modulate intestinal epithelial cell growth and migration

[4] H Iwata, et al. Brain Res. Localization of basic FGF-like immunoreactivity in the hypothalamo-hypophyseal neuroendocrine axis

[5] J W Moore, et al. Development. The mRNAs encoding acidic FGF, basic FGF and FGF receptor are coordinately downregulated during myogenic differentiation

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