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Recombinant Proteins 重组蛋白/细胞因子/生长因子 Recombinant Proteins

目录号 产品名称 产品简介
M9370 Recombinant Human TNF α (HEK293, C-His) 重组人肿瘤坏死因子α(Recombinant Human TNF α)是一个同源三聚体,它在生长调节、分化、炎性反应、病毒复制、肿瘤发生、自身免疫性疾病以及病毒、细菌、真菌和寄生虫感染中都起到重要的作用。
M9413 Recombinant Human VEGF165 Protein (HEK293, C-His) Recombinant Human VEGF165 重组人VEGF165是一种强有力的生长和血管生成细胞因子,它促进内皮细胞的增殖和存活,促进血管生成和血管通透性。
M10922 Recombinant Mouse TGF-beta 1 Protein (Human Cells) 重组小鼠TGF-beta 1 蛋白 是一种多功能细胞因子,其控制许多生物过程,包括免疫,分化,肿瘤抑制,肿瘤转移,衰老,迁移,伤口愈合,细胞凋亡,细胞分裂,脂肪生成和成骨。ED50为5-25 pg/ml
M9391 Recombinant Human TGF-β1 (HEK293, C-Fc) 重组人TGF-β1(Recombinant Human TGF-β1)是一种多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积。通过抑制 IL-4 依赖性的小鼠 HT-2 细胞的增殖能力来测定的ED50值为 ≤0.5 ng/mL。
M9241 Recombinant Human EPO Protein (HEK293, C-His) 促红细胞生成素(EPO)是肾脏在细胞缺氧时分泌的一种糖蛋白细胞因子,主要以其在促红细胞生成中的作用而闻名,它负责刺激红系祖细胞的增殖和分化。
M9402 Recombinant Human PDGF-BB Protein (HEK293, C-His) PDGF 是由两条 12.0-13.5kDa 的多肽链组成的二聚体,分别命名为 PDGF-A 和 PDGF-B 链。PDGFs、PDGF-AA、PDGF-BB 和 PDGF-AB 三种天然存在的 PDGF-AB 是多种细胞类型的有力有丝分裂原,包括平滑肌细胞、结缔组织细胞、骨和软骨细胞以及一些血细胞。
M9987 Recombinant Human PDGF-AA Protein (HEK293) 重组人PDGF-AA蛋白(Recombinant Human PDGF-AA Protein)是一种有效的促细胞分裂剂,适用于多种细胞类型,包括平滑肌细胞,结缔组织细胞,骨骼和软骨细胞以及一些血细胞。
M9981 Recombinant Human IL-11 Protein (HEK293) 重组人IL-11蛋白(Recombinant Human IL-11 Protein)是由成纤维细胞、上皮细胞和破骨细胞等基质细胞产生的一种多功能细胞因子。
M21094 Recombinant Rat IL-1β (E. coli) 白细胞介素-1β(IL-1β)是一种非分泌的促炎症细胞因子,主要由活化的巨噬细胞以及中性粒细胞、上皮细胞和内皮细胞产生。通过使用小鼠 D10S 细胞进行细胞增殖测定,ED50为 < 10.0 pg/ml,相当于比活性 > 1.0 × 108 units/mg。
M10022 Recombinant Mouse GM-CSF Protein (CHO) 重组小鼠GM-CSF蛋白是一种生长因子,可以支持粒细胞巨噬细胞祖细胞的体外集落形成。GM-CSF由许多不同的细胞类型产生,包括活化的 T 细胞、B 细胞、巨噬细胞、肥大细胞、内皮细胞和成纤维细胞等。使用小鼠 FDC-P1 细胞在细胞增殖测定中测得的ED50为<0.05 ng/ml,对应于>2.0 × 107units/mg的比活性。
M54794 Recombinant Human IL-10 (CHO) Interleukin-10 (IL-10) is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells.
M54793 Recombinant Human IL-5 (CHO) Interleukin-5 (IL-5) is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors.
M54749 Recombinant Rat IL-23 Protein (HEK293, C-His) IL-23 (IL-23 alpha & IL-12 beta Heterodimer) Protein is a recombinant protein dimer complex containing rat-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293.
M54748 Recombinant Rat IL-6 (HEK293) Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses.
M54747 Recombinant Rat IL-12 (Mammalian, C-6His) Interleukin 12 (IL-12) has important immunological functions. IL12 facilitates hematopoietic stem cell proliferation, induces NK cell proliferation, and potentiates the expansion and late activation of Th1 CD4+ T cells.
M54745 Recombinant Mouse CTLA-4 Protein (Mammalian, C-Flag) Mouse CTLA-4 is a type I transmembrane T cell inhibitory molecule. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal.
M54739 Recombinant Human ICA 512/PTPRN Protein (80AA&94AA, E.coli, N-6His) ICA 512/PTPRN Protein belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. ICA 512/PTPRN implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
M54738 Recombinant Human ICA 512/PTPRN Protein (293AA, E.coli, N-6His) ICA 512/PTPRN Protein belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. ICA 512/PTPRN implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
M54737 Recombinant Human GAD67 Protein (Baculovirus-Insect, C-His) GAD67 (GAD1) is a member of thegroup II decarboxylase family. GAD67 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker.
M54732 Recombinant Human GAS6 Protein (Mammalian, C-6His) GAS6 (Growth arrest-specific protein 6) also known as AXL receptor tyrosine kinase ligand, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest.
M54731 Recombinant Mouse GAS6 Protein (HEK293, C-His) GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells.
M54699 Recombinant Human Lactoferrin/LTF Protein (Mammalian, C-6His) Lactoferrin (LTF,乳铁蛋白) 是外分泌液中的主要铁结合蛋白,通过螯合铁和破坏细菌膜而表现出多种抗菌作用。它可以防止生物膜形成,影响骨代谢,并影响腺病毒和乳头瘤病毒感染。
M54637 Recombinant Mouse Thioredoxin/SASP Protein (E. coli) Thioredoxin/SASP 蛋白能参与多种氧化还原反应,并可利用其活性二硫醇中心进行可逆氧化和二硫键形成。它催化重要的二硫醇-二硫化物交换,并在半胱氨酸残基的 S-亚硝基化中发挥关键作用,响应细胞内一氧化氮。
M54636 Recombinant Human Thioredoxin/SASP Protein (E.coli, N-6His) 重组人Thioredoxin/SASP 蛋白能参与多种氧化还原反应,并可利用其活性二硫醇中心进行可逆氧化和二硫键形成。它催化重要的二硫醇-二硫化物交换,并在半胱氨酸残基的 S-亚硝基化中发挥关键作用,响应细胞内一氧化氮。
M54580 Recombinant Human CXCL4/PF-4 Protein (Mammalian, C-6His) Human CXCL4/PF-4 is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4/PF-4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair.
M54564 Recombinant Mouse/Rat TGF-beta 2 Protein (Mammalian) Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure.
M54561 Recombinant Mouse FABP4 Protein (HEK293, C-His) FABP4 is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family.
M54522 Recombinant Human IFN-α 2b Protein (E. coli) IFN-α 2b (Interferon-Alpha 2b) [Cys24-Glu188 (Lys46Arg)] produced by leukocytes is a member of Interferon family. IFN-alpha is mainly involved in innate immune response against a broad range of viral infections.
M49940 Recombinant Rat IL-2 (Mammalian, C-6His) Interleukin-2 (IL-2) is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
M49920 Recombinant Mouse VCAM-1 Protein (Mammalian, C-Fc) Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.









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